An innovative adaptive reuse project transforming downtown Greenville into South Carolina's life sciences destination

GREENVILLE’S HISTORIC BUILDING REIMAGINED FOR INNOVATION

GREENVILLE’S HISTORIC BUILDING REIMAGINED FOR INNOVATION

An innovative adaptive reuse project transforming downtown Greenville into South Carolina's life sciences destination

Bringing Life Sciences to Main Street

Main Street Labs is a groundbreaking 100,000-square-foot adaptive reuse project located in downtown Greenville, South Carolina, a thriving metropolitan city in the heart of the Upstate region. By repurposing a historic building with existing infrastructure, we've created one of only two locations in the United States with life sciences companies on Main Street.

This innovative approach to creating laboratory space is extremely cost-effective compared to new construction, allowing us to keep rent at lower prices for tenants so they can focus their financial resources on innovation rather than overhead. Whether through our LabAddress Program for a compliant registered address or full laboratory facilities, we support life sciences organizations at every stage.

Bringing Life Sciences to Main Street

Main Street Labs is a groundbreaking 100,000-square-foot adaptive reuse project located in downtown Greenville, South Carolina, a thriving metropolitan city in the heart of the Upstate region. By repurposing a historic building with existing infrastructure, we've created one of only two locations in the United States with life sciences companies on Main Street.

This innovative approach to creating laboratory space is extremely cost-effective compared to new construction, allowing us to keep rent at lower prices for tenants so they can focus their financial resources on innovation rather than overhead. Whether through our LabAddress Program for a compliant registered address or full laboratory facilities, we support life sciences organizations at every stage.

Built for Life Sciences Companies

An environment designed to support your work, growth, and long-term success.

Strategic Location

Work in downtown Greenville at a lower cost than major life sciences hubs while staying connected to talent, amenities, and a growing innovation ecosystem.

Community Impact

Benefit from a growing regional workforce and education pipeline that supports life sciences talent development today and into the future.

Community & Collaboration

Be part of a centralized hub where life sciences companies connect, share resources, and learn from one another to accelerate progress through proximity and collaboration.

Economic Development

Operate within a model that supports long term stability, regional investment, and growth and creates an environment where your company can scale with confidence.

Adaptive Reuse Excellence

Shared infrastructure and existing systems reduce operating costs and allow you to invest more in research, development, and growth rather than rent.

Proven Success

Join a model proven by active tenants like Kiyatec Inc., whose successful launch and expansion demonstrate the viability of operating at Main Street Labs.

Born from Collaboration. Built for Growth.

The idea for Main Street Labs was born from collaborative conversations between life sciences companies and Hughes Development. These companies faced a critical challenge: emerging laboratory-based life sciences companies often lack the physical and financial resources needed to accomplish their innovative work, especially in regions outside major biotech hubs.

While South Carolina offers significant economic advantages for life sciences companies, available laboratory space for small to medium-sized companies in the Upstate was scarce. Both Greenville and South Carolina had strategic economic development goals to grow life sciences by attracting and nurturing companies, but lacked the infrastructure to support these goals.

Main Street Labs was developed to fill this need. By locating our laboratory hub on Main Street in downtown Greenville, we've positioned South Carolina's life sciences sector in the same prestigious arena as Cambridge, Massachusetts, the only other U.S. location with life sciences companies on Main Street. Today, with anchor tenant Kiyatec Inc. and growing community of innovators, we're proving that world-class life sciences innovation can thrive in the heart of the South.

Join leading life sciences organizations who chose Main Street Labs to eliminate infrastructure barriers and focus on what matters: groundbreaking discoveries

Ready to Accelerate Your Research?

Ready to Accelerate Your Research?

Join leading life sciences organizations who chose Main Street Labs to eliminate infrastructure barriers and focus on what matters: groundbreaking discoveries

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